RIKEN researchers have shown how a gene-reading enzyme manages to dismantle bead-like structures of DNA and reassemble them at high speed, without disrupting the integrity of genomic organization 1.

Since many years PCR methods and protocols are part of standard research, diagnostic assays and projects in academia and industry. The scope of applications is getting a standard on global level more ...

Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA and RNA. PCR involves the enzymatic amplification of ...

Showtime! The movie zooms right into a cell nucleus. Like a screw, the DNA double helix propels into the active centre of the RNA polymerase. “There, it is unwound, and one of the two DNA strands then ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...

AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But ...