Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical ...

The research group led by Professor Tsutomu Suzuki of The University of Tokyo is opening new horizons in RNA modification research. In particular, the group has discovered a reversible RNA ...

To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...

To overcome these limitations, the research team developed a "targeted RNA acetylation system (dCas13-eNAT10)" by combining Cas13, gene scissors that precisely target desired RNA, with a hyperactive ...

< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

RNA modifications play crucial roles in gene regulation, cellular function and the response to environmental stimuli. However, the detection and characterization of these modifications remain ...

This comprehensive review by Prof. Zili Zhang, Prof. Mei Guo, and their collaborators at Nanjing University of Chinese Medicine systematically outlines the dual role of m⁶A modification in promoting ...

Schematic depiction of the principal components of epitranscriptomic mechanisms and their involvement in malignant hematopoiesis. Writers and erasers of main reversible methylations are represented in ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

This project aims to unveil physiological roles of RNA modifications associated with fundamental biological processes. We search for novel RNA modifications from human cells and other organisms, and ...