－スプライソスタチンAの強い抗がん活性の解明に迫る－ 理化学研究所（理研）環境資源科学研究センターケミカルゲノミクス研究グループの吉田稔グループディレクター、芳本玲特別研究員（研究当時）、チピ・シュレスタ・ジャガット特別研究員 ...
Pre-mRNA splicing is a fundamental step in mRNA maturation and its discovery in 1977 revolutionized our understanding of gene expression. This collection includes reviews and research articles from ...
－1細胞完全長トータルRNAシーケンス法の開発に成功－ 要旨 理化学研究所（理研）情報基盤センター バイオインフォマティクス研究開発ユニットの林哲太郎センター研究員、尾崎遼基礎科学特別研究員、二階堂愛ユニットリーダーらの研究チーム ※ は ...
A wide spectrum of cancer-associated genetic alterations, including those that result in changes to the splicing of pre–messenger RNA (mRNA), can lead to the presentation of aberrant peptides as ...
The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...
FUSは転写、選択的スプライシングおよびmRNAの輸送を調節するRNA結合タンパク質である。FUSの異常が家族性および孤発性ALS ...
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...
Bristol-Myers Squibb’s quest to claim dominance in the immunotherapy space continues through a new collaboration with Eisai and its US-based precision medicine subsidiary H3 Biomedicine to evaluate ...
In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led by LI Ming ...
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