When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits that RNA before it is translated into protein. Many genes can be processed and ...
The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...
Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
Researchers at the University of Barcelona reveal that RTP801, a protein elevated in Alzheimer’s patients, disrupts RNA processing and protein synthesis, exacerbating cognitive decline. This discovery ...
New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during ...
A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...