Premature termination of transcription influences ribosomal RNA output and RNA polymerase I drug sensitivity, revealing a mechanism of resistance to transcription-targeting chemotherapy.

Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...

He ripped the ribosome open, literally. And, it became an important step in the production of antibiotics. In 2000, using a method known as x-ray crystallography, Venkatraman Ramakrishnan and other ...

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell’s protein-making machinery. rRNA accounts for much of the RNA in a cell, and it’s crucial for life. “It’s ...

Hyperthermophilic archaea are true survival experts. They thrive in boiling hot springs and deep-sea vents—environments lethal to nearly all other forms of life. Subscribe to our newsletter for the ...