The aminoacylation reaction, which is catalysed by aminoacyl-tRNA synthetases (aaRSs), fuses each amino acid to its cognate tRNA. This reaction requires amino acid activation through condensation of ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

理化学研究所（理研）脳神経科学研究センタータンパク質構造疾患研究チームのチェンウェン・チェン研究員と田中元雅チームリーダーの研究チームは、タンパク質合成中の転移RNA（tRNA）[1] の種類や量を詳しく解析する「tRNAリボソームプロファイリング法 ...

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Rensselaer Polytechnic Institute's ...

New findings indicate that transfer RNA (tRNA) has another function in addition to its long-established role in gene expression. tRNA also helps control apoptosis, or programmed cell death, according ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Kumamoto [Japan] September 30 (ANI): A pioneering study undertaken by a Kumamoto University research team shed light on the crucial role of TRMT10A, a tRNA methylation enzyme, in sustaining brain ...

Boston, Massachusetts--(Newsfile Corp. - April 29, 2025) - Tevard Biosciences, Inc., a privately held biotechnology company pioneering tRNA-based therapies to cure a broad range of genetic diseases, ...

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the ...

A novel tRNA fragment limits UV-driven photoageing by protecting collagen and mRNA stability. Discover the mechanism and its therapeutic potential. Read more.

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...