Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding ...
Figure 2: Signal-to-noise ratio for vertebrate microRNA target site predictions. It has been proposed that microRNAs can target genomic DNA in animals and induce transcriptional silencing of genes ...
A DNA nano-harvester stays on its track inside tumor cells, measuring cancer aggressiveness by detecting a key microRNA ...
Background: The regulation of target gene mRNA mediated by microRNA may play an important role in glucose metabolism in fish. Previous research findings of our research group revealed that Momordica ...
MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both ...
The interaction of circulating cells within the vascular wall is a critical event in chronic inflammatory processes, such as atherosclerosis, but the control of the vascular inflammatory state is ...
Correspondence to Dr Guisheng Song, Department of Medicine, University of Minnesota Twin Cities, 516 Delaware Street SE, Minneapolis, Minnesota, USA; gsong{at}umn.edu Objective Kupffer cells (KCs) ...
The 2024 Nobel Prize in physiology or medicine has been awarded to US scientists Victor Ambros and Gary Ruvkun for their work on the discovery of microRNA, a molecule that governs how cells in the ...
Andrea Kasinski receives funding from the National Institutes of Health, Department of Defense, and the American Lung Association. She is the inventor on multiple patients associated with her ...
Genetic and biochemical analyses reveal that two stem-cell-specific microRNAs control stem cell fate decisions between pluripotency and differentiation through repressing Ago2, a key component of the ...
Identifying targets is critical for understanding the biological effects of microRNA (miRNA) expression. The challenge lies in characterizing the cohort of targets for a specific miRNA, especially ...